Important task

Mon, 11/20/2023 - 13:30
Kod CSS i JS

“My main task for the nearest future is to make sure that the NCN budget is increased significantly, by approx. PLN 300 million”, says Prof. Krzysztof Jóźwiak speaking to “Forum Akademickie”. An interview with the NCN Director was published on 20 November.

We have been talking about NCN’s extremely low budget for many months. Funding awarded to the NCN in no way meets the needs of the Polish scientific community. Less and less applicants receive funding for their research. The calls concluded in the nearest future will have a single digit success rate.

Prof. Krzysztof Jóźwiak has been the NCN Director since 30 October. He had to wait eight months for his official appointment. In hist first interview in the new capacity, he talks about, inter alia, the significance of grants for research, indirect costs and NCN’s low budget consequences for research and the entire country.

“If [our] budget for 2024 is not increased, we might need to end some schemes or continue to decrease funding for the OPUS call which would be to the great detriment of Polish science. I will also argue that NCN’s grant-in-aid must be increased on a regular basis to allow the NCN to plan its statutory operations in the long run and to ensure sufficient funds for research to the scientific community.

Prof. Jóźwiak underlines that researchers working in Poland are involved in more and more ambitious projects, their competencies are higher and higher and Polish science is in a completely different place than it was over ten years ago, when the National Science Centre was established.

“In the past, it was widely believed that research ideas must be adjusted to financial capabilities. For over 10 years of NCN’s operation researchers have learnt to pursue more extensive and ambitious research, develop bigger projects based on external funds awarded in the calls for proposals. They are not afraid to compete for such funds, presenting bold projects and using more and more interesting techniques, in wide international collaboration which is so important for research. At the NCN, we respond to the needs and ambitions of Polish science (…). We believe it to be our great success although it is not supported by an increased funding.

Prof. Krzysztof Jóźwiak talked to Piotr Kieraciński. The whole text is available on the website of “Forum Akademickie.”

Results of the international JPND 2023 Call

Mon, 11/20/2023 - 11:00
Kod CSS i JS

Three research projects involving Polish researchers have been awarded funding in a call launched by the JPND network (EU Joint Programme – Neurodegenerative Disease Research). Polish research teams will receive over PLN 3 million for research on neurodegenerative diseases, such as Alzheimer’s disease or Creutzfeldt-Jakob disease.

Three research projects have been recommended for funding in the call for international research projects with the aim of improving the understanding of the complex and multifactorial pathogenesis of neurodegenerative diseases. The call entitled Large scale analysis of OMICS data for drug-target finding in neurodegenerative diseases has been launched by the JPND network, which includes the NCN.

Funding proposals could be submitted by international consortia composed of at least 3 research teams from at least 3 countries participating in the call (Austria, Belgium, Czech Republic, France, Germany, Hungary, Ireland, Israel, Italy, Canada, Luxembourg, Netherlands, Poland, Slovakia, Spain, Sweden, Turkey).

Polish research teams will be awarded a total of over PLN 3 million for their research projects.

The winning projects:

  • CCAD – Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identification and Biomarkers Development

Prof. Krzysztof Sobczak from the Adam Mickiewicz University in Poznań is the principal investigator of the Polish research team.

Researchers participating in the project will try to decipher molecular targets and mode of action of low molecular weight compounds that are drug candidates for Alzheimer’s disease. The consortium members have already analysed five compounds as such. In the CCAD project, researchers will also try to identify diagnostic or theragnostic clinical biomarkers for Alzheimer’s disease through the analyses of big data, including data collected in the course of the project. 

  • PRIONOMICS: Prioritizing diagnostics and therapeutics of human prion diseases through integrative omics  

Prof. Beata Katarzyna Sikorska from the Medical University of Lodz is the principal investigator of the Polish research team. 

The purpose of the project is to identify the underlying mechanisms that lead to the development and progression of sporadic Creutzfeldt-Jakob disease (sCJD). For this purpose, new and existing data will be collected from patients with prion diseases. Researchers will put strong emphasis on identification of dysregulated pathways involved in age at onset and/or disease progression rate. They are also intending to develop new blood-based biomarkers for persons at risk and therapeutic drug targets for CJD.

  • MyRIAD: (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer’s disease and Dementia.

Dr Agnieszka Fiszer from the Institute of Bioorganic Chemistry, Polish Academy of Sciences is the principal investigator of the Polish research team.

Researchers involved the project will look for possibilities of early detention of neurodegenerative conditions, such as Alzheimer’s disease (AD). For this purpose, they will analyse microRNAs (small non-coding RNAs) as non-invasive biomarkers of neurodegenerative diseases and will try to identify new therapeutical targets – genes associated with neurodegeneration. The project will enhance current understanding of neurodegenerative conditions.

Winners of JPND 2023 Call include 10 research projects evaluated and recommended for funding by the international panel of experts following a peer-review. Projects involving Polish research teams will be coordinated by the research teams from France, Germany and Ireland.   

The call results are available on the website of the network

JPND Call 2023 Text

Pre-announcement of 17th JPIAMR transnational call for research projects within the ERA-NET JPIAMR-ACTION

Mon, 11/20/2023 - 10:59
Kod CSS i JS

It is our pleasure to announce that JPIAMR (Joint Programming Initiative on Antimicrobial Resistance) will launch in 2024 an international call for projects within the framework of the ERA-NET JPIAMR-ACTION.

The call Interventions Moving forward to Promote ACTion to counteract the emergence and spread of bacterial and fungal resistance and to improve treatments (IMPACT) will involve funders from 19 countries.

The total estimated call budget is about 19 million euro. The Polish research teams may claim up to 0,5 M euro allocated to the call by the Council of the National Science Centre.

The primary aim of the call is to take action against the growing global threat of increased spread of antimicrobial (antibacterial and antifungal) resistance by funding international collaborative research projects aiming to improve, compare and evaluate the effectiveness, cost effectiveness, and uptake of existing interventions against bacterial or fungal infections and/or to design new interventions against fungal infections.

Timeline

The call Interventions Moving forward to Promote ACTion to counteract the emergence and spread of bacterial and fungal resistance and to improve treatments will follow a two-step evaluation procedure.

  • 10 January 2024 – launch of the call and Partner Search Tool
  • 24 January 2024 – webinar for applicants
  • 14 March 2024 – deadline for pre-proposals
  • 9 July 2024 – deadline for full proposals
  • 16 July 2024 – deadline for submission of proposals to NCN (via OSF)

More information about the call is available at https://www.jpiamr.eu/calls/amr-interventions-call-2024

Please note that the information provided in the pre-announcement is not binding and that changes may occur without notice until the call opening on 10 January 2024.

Origins and development of peripheral academic capitalism in Poland

Principal Investigator :
Dr Krystian Szadkowski
Adam Mickiewicz University Poznań

Panel: HS6

Funding scheme : SONATA BIS 12
announced on 15 June 2022

Why is it that after many years of trying to mobilise Polish academics to publish in top international journals, 1/3 of all publications by Polish authors in the Web of Science database in 2022 were articles published by one publisher with a dubious reputation? Why were the last two decades of calls for Polish universities to catch up with the West accompanied by their successive and dramatic fall in all global university rankings?

Dr Krystian Szadkowski, photo by Michał ŁepeckiDr Krystian Szadkowski, photo by Michał Łepecki To answer these questions, it is not enough to focus on factors such as insufficient funding, differences in mindset or excessive bureaucracy. It is necessary to go back to the source. Since the very start of capitalist transformation, all modernisation efforts in Polish science and higher education have been aimed at aligning the system with the Western model. However, the system was and continues to be very different, and this calls for a serious theoretical analysis and explanation.

The goal of this project is to elucidate the specifics that determined the origin and development of the peculiar form of capitalism in Polish science and higher education between 1990 and 2021. Our aim is to develop a new theory to systematically capture its dynamics in terms of peripheral academic capitalism, i.e., a system whose conditions and patterns of production differ, in essence and structure, from those of the centre. A complementary objective is to study the role of international organisations (such as the OECD and the World Bank) in the development of this phenomenon, the role and scale of resistance from students and academics, and the influence of large commercial academic publishers on policy-making in the sector.

The project will collect extensive data on the capitalist reality of Polish science and higher education and how it works, which will furnish the basis for a new theory of peripheral academic capitalism. We will present the main actors and narratives responsible for the shape that academic capitalism has taken in Poland. We will look into the public policies that aimed to transform the sector into a robust system of academic capitalism, determine who was responsible for the discourses developed within it, and how these were shaped by international organizations such as the OECD or the World Bank. We will analyse the resistance with which these changes were met among students and academics and the role of private capital, concentrated mainly in the sector of large commercial academic publishers, in shaping its current form. Last, but not least, we will analyse to what extent and why the form of academic capitalism that emerged in Poland differs from the one present in the countries that are at the centre of the capitalist world-system. The project will allow us to step beyond the unproductive dichotomy of modern debates on sector transformation, which often pits liberal modernisers, who want to copy ready-made solutions from central countries, against conservatives, who oppose the subordination of “Polish science” to Western models.

Project title: Origins and development of peripheral academic capitalism in Poland (1990-2021)

Dr Krystian Szadkowski

Kierownik - dodatkowe informacje

He earned his PhD at the Adam Mickiewicz University in Poznań (UAM), while working at the Education International research institute in Brussels within the framework of the Marie Curie-Skłodowska network. He was postdoctoral visiting researcher at the Centre for Global Higher Education, both at University College London and University of Oxford. His work is focused on developing new theoretical languages and methods for the study of science and higher education. He is a member of the AMU’s Scholarly Communication Research Group.

Dr Krystian Szadkowski, photo by Michał Łepecki

Relaxing NCN’s Open Access Policy – webinar materials

Thu, 11/16/2023 - 15:39
Kod CSS i JS

We have published a video and presentation from the webinar of 30 October on the relaxation of NCN’s Open Access Policy.

During the meeting, Aneta Pazik-Aybar and Gabriela Czarny from our Open Access Team talked about the relaxation of NCN’s Open Access Policy and answered questions and queries of researchers and administrative staff. You can watch a video from the meeting on our YouTube channel and on our website in the Open Access tab where you can also find and download a presentation on the subjects discussed at the webinar.

There was also time for questions and answers which will be published as FAQ at a later date. We will also explain any issues raised at the meeting that we did not have time to address.

Weave-UNISONO: launch of a call for proposals with the Slovenian ARIS as the lead agency

Wed, 11/15/2023 - 17:00
Kod CSS i JS

We are pleased to announce that between 14 November 2023 and 12 January 2024, a call for proposals will be open at the Slovenian agency ARIS within the framework of the Weave Programme, with the Slovenian agency acting as the lead agency.

Under the Weave-UNISONO call, if a joint proposal must be submitted to ARIS as the lead agency by 12 January 2024, an NCN proposal must be submitted electronically via the OSF submission system as soon as possible following the submission of the joint proposal to ARIS, by 19 January 2024, 23:59 p.m. at the latest.

PLEASE NOTE: Once the work on the NCN proposal has started in the OSF submission system, the Polish research team has 45 calendar days to complete the proposal and submit it to the NCN. After that, the proposal can no longer be edited, in which case a Polish research team that has not sent its proposal to the NCN must prepare a new proposal and complete it in the OSF submission system.

PLEASE NOTE: NCN proposals processed in the OSF submission system in 2023, with an exchange rate of 1 EUR = 4.7244 PLN, must be completed in and submitted via the OSF submission system by 31 December 2023, 23:59:59. Otherwise, the proposal can no longer be edited, in which case a Polish research team must prepare a new proposal (with an exchange rate of 1 EUR = 4. 5940 PLN) and complete it in the OSF submission system. If a joint proposal has already been submitted to the lead agency, with the budget of the Polish part of the project calculated according to another exchange rate, the NCN proposal will be inconsistent with the joint proposal and may result in the proposal being rejected on the grounds that it does not meet the eligibility criteria.

OPUS 24+LAP/Weave: the latest results

Wed, 11/15/2023 - 14:00
Kod CSS i JS

21 more Polish teams will conduct their research in tandem with German, Slovenian, Austrian and Czech partners under the OPUS 24+LAP/Weave scheme. The NCN has slated a total of more than 33.7 million zlotys in funding for their projects. Meet the latest winners.

Of all calls in the NCN portfolio, OPUS has the broadest formula, targeting researchers at all stages of their academic career. In its 24th round, researchers working at Polish research institutions could win funding not just for domestic research projects, but also wider international ventures based on the Lead Agency Procedure (LAP). Under LAP, they could plan their research in cooperation with teams from Austria, Czech Republic, Slovenia, Germany, Switzerland, Luxembourg or Belgium-Flanders.

As the Lead Agency in the programme, the National Science Centre was responsible for the full merit-based evaluation of all proposals, which then had to be approved by international partner agencies. The Polish teams will be funded by the NCN, while their partners’ funding will come from their respective institutions in Germany, Slovenia, Czech Republic and Austria.

Bi- and trilateral projects

The ranking list features 13 bilateral projects with Germany, 5 bilateral projects with Slovenia, and 3 trilateral projects: Polish-German-Austrian, Polish-Slovenian-Austrian, and Polish-Slovenian-Czech, in different research disciplines: 3 in Arts, Humanities and Social Sciences, 5 in Life Sciences, and 13 in Physical Sciences and Engineering.

In Arts, Humanities and Social Sciences, Dr hab. Anna Horolets from the University of Warsaw has teamed up with Prof. Alexandra Nadine Schwell from the University of Klagenfurt and Prof. Saša Poljak Istenič from the Research Centre of the Slovenian Academy of Sciences and Arts to study the European policy of climate-neutrality for cities and its local interpretations. They will analyse which climate-change issues are seen as especially urgent in several cities that have joined the EU Mission 100 action, which aims to deliver 100 climate-neutral cities by 2030. The researchers will be following the process of transition toward climate neutrality in Warsaw, Klagenfurt and Lubljana. The NCN has awarded more than 1.2 million zlotys to the Polish part of the project.

In the Life Sciences panel, researchers from Poland and Slovenia will work on a project focused on the development of new therapies for inflammatory diseases. Chronic inflammation is involved in the pathogenesis of various disorders, such as arthritis, arterial sclerosis, irritable bowel syndrome, cancer and even depression. Dr hab. Anna Więckowska from the Jagiellonian University Medical College and Prof. Izidor Sosič from the University of Ljubljana will join forces to obtain the first-in-class anti-inflammatory PROTAC molecules that can degrade protein kinases TAK1 and IKKβ. The project was awarded more than 2 million zlotys in funding by the NCN.

Winners in Physical Sciences and Engineering include a Polish-German project to be hosted by the Nicolaus Copernicus Astronomical Center, PAS, headed by Dr. hab. Rodolfo Henrique Smiljanic, in cooperation with Prof. Norbert Christlieb from Heidelberg University.  Entitled “The old Milky Way: a holistic approach for the accurate analysis of metal-poor stars”, this innovative project will try to identify the precise atmospheric parameters of metal-poor stars and their chemical composition. These findings will then help them reconstruct the properties of the first sources of chemical elements of stellar origin in the Universe. The budget of the Polish part of the project is more than 2 million zlotys.

Lead Agency Procedure – LAP

In the latest OPUS 24+LAP/Weave call researchers could request funding for projects conducted without international partners, as well as bilateral or trilateral LAP projects involving foreign cooperation or access to large international research equipment. The call was open to researchers at every stage of their academic career. LAP is a new proposal evaluation standard adopted by European research-funding institutions, designed to facilitate the funding proposal process for international research teams and streamline proposal review.

The domestic part of OPUS 24+LAP/Weave concluded in May. Ranking lists for partner countries under the LAP procedures are being successively published as their funding-agencies approve the results.

Decisions and their delivery

All the positive and negative decisions for OPUS LAP proposals recommended for funding under OPUS LAP in cooperation with German Research Foundation (DFG), Slovenian Research Agency (ARIS), DFG and the Austrian Science Fund (FWF), ARIS and the Czech Science Foundation (GACR) and ARIS and FWF were sent out today. The decisions of the NCN Director are served on the applicant electronically, to the e-mail address indicated in the proposal.

If the applicant is an entity referred to in Article 27 (1)-(7) and (9) of the Act on the National Science Centre, the decision will only be delivered to the Electronic Delivery Inbox (ESP ePUAP) provided in the proposal. If the applicant is a natural person and has listed an ePUAP address in the proposal, the decision will be sent to that address. Otherwise, a message will be sent to the applicant’s indicated e-mail account, containing a link from which the decision of the NCN Director can be downloaded.

The funding decisions of the Director of the National Science Centre are also communicated to the principal investigator and, if the applicant is a natural person, to the host institution indicated in the proposal.

If you do not receive a decision, please make sure that the address (ESP, ePUAP, e-mail) listed in your proposal is correct. If not, contact the person in charge of the proposal, as indicated in the OSF system.

Quantum Technologies Public Policies Report 2023

Wed, 11/15/2023 - 10:14
Kod CSS i JS

Europe is strong-willed to boost European scientific advantage and excellence in Quantum Technologies (QT), and to expand a competitive European industry in QT creating environment where quantum innovation can thrive attracting investments in this field. National policies act as the foundation upon which Europe's quantum future is built. They provide the necessary framework for countries to invest strategically, collaborate effectively, and contribute to the European leadership in QT.

The QuantERA research funding programme, which brings together the scientific community, funding agencies, and industry representatives to leverage transnational cooperation in QT, continuously monitors the evolving landscape of national quantum programmes and approaches.  

In 2023 QuantERA mapped and illustrated developments in QT programming in the second edition of the report Quantum Technologies Public Policies in Europe. The publication delivers a snapshot of the European policies, as well as funding instruments provided by relevant Research Funding Organisations. It gives a comprehensive view of the current quantum landscape, offering valuable data and analysis, which can serve as a reference and toolkit for policymakers to shape the future development of QT at national and the European level.

The report is the result of the joint efforts of the QuantERA Consortium partners, supported by the EC and the QT Flagship. It summarizes the findings from an inventory conducted among 31 European Union member states and associated countries. In addition to an overview of national and regional policies for QT, the publication includes information on new developments with regard to the previous publication –  Quantum Technologies Public Policies in Europe, 2020.

While providing an overview of the current state of QT in Europe, QuantERA’s report points also the readers to the horizons of the field’s landscape enabling them to look beyond and identify the next steps forward to increase European potential in QT.

Results of the international call on urban issues and challenges

Tue, 11/14/2023 - 12:00
Kod CSS i JS

The JPI Urban Europe Network has concluded its BTC ENUTC Call 2023. The winners include two international research projects involving researchers from Poland. PLN 1.3 million will be awarded for research. 

The JPI Urban Europe supports researchers pursuing international interdisciplinary research projects responding to the challenges of cities and urban areas. The call launched this year (Building transformation capacity through arts and design: Unlocking the full potential for urban transitions) was focused on urban development and development of urban areas. 

The BTC ENUTC call was open to researchers working in the Polish research institutions and intending to pursue international research projects in partnership with researchers from Belgium. Bulgaria, Latvia, the Netherlands, Romania or Sweden.

The winning applicants included five international research projects, two of which involved researchers from Poland. They will be awarded over PLN 1.3 million.

  • unLoc – Exploring the synergy of human and machine creativity in architecture. Redesigning urban space through machine learning, artistic expression, and community collaboration.

    Jacek Złoczowski from the Pedagogical University of Krakow is the principal investigator of the Polish research team. The project budget is over PLN 900,000.

    The project aims to develop a method of redesigning cities and buildings with a difficult history by using post-communist architecture as an exemplary manifestation and redefining their form and meaning. Researchers will recommend new functions and strategies of transformations of buildings to adjust them to the needs of their residents. In the project, they will use the machine learning algorithms that will help them create alternative pictures of urban areas. 

  • The Urban Food Factory (Miejska Fabryka Żywności) – A web-based decision support manual to reuse inner-city multi-storey carparks for controlled environment agriculture.

    Monika Anna Szopińska-Mularz from the z Rzeszów University of Technology is the principal investigator of the Polish research team. The project will be awarded funding of nearly PLN 415,000.

    The project aims to demonstrate how adaptive reuse of car parking structures for controlled environment agriculture can strengthen urban social, economic and environmental resilience. A web-based decision support manual will be developed for the creation of Urban Farming Living Labs. Interactive 3D models will be created to improve understanding of the concept.

NCN within the JPI Urban Europe network

The National Science Centre has cooperated with the JPI Urban Europe Network since 2015 in the organisation of calls for proposals aimed at researchers pursuing international research projects in the area of urban issues and challenges. So far, Polish researches have had an opportunity to apply for funding in seven calls of JPI Urban Europe.

Extracellular vimentin: a significant factor of brain damage in COVID-19

Principal Investigator :
Łukasz Suprewicz
Medical University of Bialystok

Panel: NZ6

Funding scheme : PRELUDIUM 21
announced on 15 march 2022

The SARS-CoV-2 virus, responsible for the outbreak of the COVID-19 pandemic in 2020, has had a huge impact on worldwide healthcare systems. Although it was initially seen as a factor of respiratory infection, it soon turned out it may also lead to severe damage to the central nervous system (CNS). Up to 40% of patients experience chronic neurological symptoms, commonly referred to as "Covid brain fog”. Although some of these (e.g., dizziness) are relatively mild, some patients develop serious sequelae, such as stroke or encephalopathy (brain damage). In light of the ongoing SARS-CoV-2 pandemic, it is crucial to understand the mechanism behind this damage and develop effective treatments.

How SARS-CoV-2 affects the brain remains a subject of intensive research. One hypothesis points to the excessive secretion of inflammatory mediators, known as the “cytokine storm” and the direct action of protein S, which the virus uses to enter host cells. These processes are indicated as some of the factors that damage the barrier between the blood and the structures of the brain (the so-called blood-brain barrier), allowing harmful substances, such as viruses and inflammatory proteins, to pass through in increased quantities.

It is in this context that vimentin makes an appearance. Vimentin is a protein that builds the cytoskeleton of most cells, where it plays a key role in fundamental processes, such as cell division, migration and the protection of the cell nucleus from mechanical damage. When released into the bloodstream by immune cells in response to inflammation, it is known as extracellular vimentin. There are two forms of extracellular vimentin: that which is bound or unbound to the cell surface. In an earlier project, we showed that extracellular vimentin acts as a co-receptor for SARS-CoV-2, which means it is necessary for a cell to be effectively infected (Suprewicz et. al. Small 2022).

Łukasz Suprewicz, photo by Michał ŁepeckiŁukasz Suprewicz, photo by Michał Łepecki The purpose of this project is to focus on the role of extracellular vimentin in CNS inflammation associated with a SARS-CoV-2 infection. We investigate the impact of extracellular vimentin on different cell types present in the brain, such as endothelial cells and astrocytes, using a 3D blood-brain barrier flow model to assess the permeability and integrity of endothelial cells, and the adhesion and migration of immune-response cells in the presence of vimentin and the SARS-CoV-2 protein. In the next stage, we will evaluate the impact of the substances in question on inflammation by analysing the secretion of inflammatory mediators. The study will culminate in a molecular-level assessment of the signaling pathways characteristic of SARS-CoV-2 infections and inflammatory blood vessel damage.

The project may significantly increase our knowledge of the effects of extracellular vimentin and its modified forms on endothelial and immune cell responses in a SARS-CoV-2 infection. This, in turn, may contribute to developing more effective treatments for COVID-19 patients, especially those with neurological complications. The project may also identify new therapeutic targets to help fight potential future global pandemics, considering that the role of extracellular vimentin as a co-receptor is not restricted to SARS-CoV-2 but also applies to other infections, including those caused by bacteria.

Diapedesis of human neutrophils, untreated or stimulated by vimentin (Vim), citrullinated vimentin (CitVim), or lipopolysaccharide (LPS) in a 3D model of blood vessels. Neutrophil elastase (green), actin (red), DNA (blue).

Diapedesis of human neutrophils, untreated or stimulated by vimentin (Vim), citrullinated vimentin (CitVim), or lipopolysaccharide (LPS) in a 3D model of blood vessels. Neutrophil elastase (green), actin (red), DNA (blue)..

Project title: Extracellular vimentin as a signaling molecule in the pathogenesis of inflammation and central nervous system damage in patients with COVID-19

Łukasz Suprewicz

Kierownik - dodatkowe informacje

Graduate of the Medical University of Białystok and laboratory diagnostician. PhD student (4th year) at the Doctoral School of the Medical University of Białystok. Author and co-author of over twenty publications in international press/ journals. His research focuses on the molecular mechanisms of interaction between proteins, pathogens and immune-response cells. PI in a PRELUDIUM 21 project and member of a PRELUDIUM BIS1 team, headed by Prof. Dr hab. Robert Bucki.

Łukasz Suprewicz, photo by Michał Łepecki